Anionic polymers. I. Inhibition of prostatic acid phosphatase.
نویسندگان
چکیده
In the course of synthesizing a number of aryl phosphate esters as substrates for prostatic acid phosphatase, polymeric phosphorylated products obtained by reaction of 4,4’-dihydroxybiphenyl with phosphorus oxychloride were found to be potent enzyme inhibitors. This report describes the preparation of these anionic polymers and some characteristics of their inhibition of prostatic acid phosphatase which seem to resemble the inhibition of hyaluronidase and alkaline phosphatase by a number of polyarylphosphate compounds (1, 2).
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 233 3 شماره
صفحات -
تاریخ انتشار 1958